Colorimetric estimation of vancomycin using modified silver nanoparticles and implementing it on various types of pharmaceutical perpetrations

Abstract. Al-Karami MA, Al-Rufaie MM. 2022. Colorimetric estimation of vancomycin using modified silver nanoparticles and implementing it on various types pharmaceutical perpetrations. Nusantara Bioscience 14: 70-77. The current research proposes a simple, quick, sensitive method for determining the pure state (Van) several its medicinal formulations. antibiotic is an effective reduction agent diluting ore mineral salt from nitrate (Ag+) to nanoparticles. Polyvinylpyrrolidone was used as stabilizer in medium sodium hydroxide base. highest absorption oxidation-reduction product occurs at 440 nm. calibration curve measured, following data generated, indicating that Beer-Lambert Law followed within concentration range 2.5-70 parts per million. Sandal's molar absorptivity 2.0043 x 104 L/mol.cm, sensitivity 0.0723 g/cm2. correlation coefficient 0.9987, standard deviation rate 0.402%. biological influence Gram-positive Gram-negative bacteria researched, efficacy samples prepared these has shown be promising.